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Rabbit Anti-SHISA5/AP Conjugated antibody (bs-23909R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23909R-AP
英文名稱1 Rabbit Anti-SHISA5/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的SHISA5蛋白抗體
別    名 pProtein shisa 5; Putative NF kappa B activating protein 120; Putative NFkB activating protein 120; Scotin; Shisa homolog 5 (Xenopus laevis); SHSA5_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SHISA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Constituents: 0.05M TBS, pH 8.0 with 10mg/ml BSA and 0.05% NaN3, 50% glycerol. Or Lyophilized. Buffer = 0.05M TBS, pH 8.0 with 10mg/ml BSA and 0.05% NaN3. Reconstitute with sterile distilled water.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Function:
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.

Subunit:
Interacts with PDCD6; PDCD6 can stabilze SHISA5.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane.

DISEASE:
Induced in a p53/TP53-dependent manner in response to cellular stress.

Database links:

Entrez Gene: 51246 Human

Omim: 607290 Human

SwissProt: Q8N114 Human

Unigene: 414579 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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