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Rabbit Anti-NUDT16/Biotin Conjugated antibody (bs-24115R-Bio)
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-24115R-Bio
英文名稱1 Rabbit Anti-NUDT16/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的NUDT16蛋白抗體
別    名 FLJ31265; FLJ34034; FLJ36248; Nucleoside diphosphate-linked moiety X motif 16; NUD16_MOUSE; Nudix (nucleoside diphosphate linked moiety X) type motif 16; Nudix motif 16; NUDT 16; NUDT16; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse NUDT16
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
NUDT16 (Nudix Hydrolase 16) is a Protein Coding gene. Among its related pathways are Metabolism and Purine metabolism (KEGG). GO annotations related to this gene include protein homodimerization activity and hydrolase activity. An important paralog of this gene is NUDT16L1.

Function:
RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro).

Subcellular Location:
Nucleus > nucleolus. Nucleus > nucleoplasm. Predominantly localized in nucleolus, and in a minor proportion in distinct foci in the nucleoplasm.

Similarity:
Belongs to the Nudix hydrolase family.
Contains 1 nudix hydrolase domain.

Database links:

Entrez Gene: 131870 Human

Entrez Gene: 75686 Mouse

Entrez Gene: 363129 Rat

SwissProt: Q96DE0 Human

SwissProt: Q6P3D0 Mouse

SwissProt: B2RYV2 Rat

Unigene: 282050 Human

Unigene: 305810 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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