| 產(chǎn)品編號(hào) | bsm-36100M-Gold |
| 英文名稱1 | Mouse Anti-AD7c-NTP/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的神經(jīng)絲蛋白單克隆抗體 |
| 別 名 | neuronal thread protein AD7c-NTP; AD7c-NTP. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 |
| 抗體來(lái)源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | 4E7 |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | Recombinant human AD7C NTP full length protein |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein G |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease. Database links: GenBank: AAC08737 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. AD7C-NTP是存在于神經(jīng)元中的一種41Kda的蛋白質(zhì)，在AD患者腦內(nèi)選擇性升高，和其病理過(guò)程相關(guān)，AD7C-NTP基因也只在神經(jīng)元表達(dá)，AD患者腦脊液中AD7C-NTP表達(dá)升高， AD7C-NTP作為AD早期診斷和確診的生物化學(xué)標(biāo)志正引起越來(lái)越多的關(guān)注. |
