| 產(chǎn)品編號 | bs-4349R-Gold |
| 英文名稱1 | Rabbit Anti-ZNF658/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的鋅指蛋白658抗體 |
| 別 名 | DKFZp572C163; FLJ32813; MGC35232; Zinc finger protein 658; ZN658_HUMAN; ZNF658. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Chimpanzee, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 122, 71kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF658 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: ZNF658 (Zinc Finger Protein 658) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF208. Function: Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3) found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply. Subcellular Location: Nucleus. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 24 C2H2-type zinc fingers. Contains 1 KRAB domain. Database links: Entrez Gene: 26149 Human SwissProt: Q5TYW1 Human Unigene: 522147 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
