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Rabbit Anti-PNPLA3/Gold Conjugated antibody (bs-12745R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12745R-Gold
英文名稱 Rabbit Anti-PNPLA3/Gold Conjugated antibody
中文名稱 膠體金標記的脂肪營養(yǎng)素PNPLA3抗體
別    名 Acylglycerol O acyltransferase; Adiponutrin; ADPN; C22orf20; Calcium independent phospholipase A2 epsilon; DJ796I17.1; iPLA(2)epsilon; IPLA2-epsilon; Patatin like phospholipase domain containing 3; patatin like phospholipase domain containing protein 3; phospholipase A2, calcium independent, epsilon.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  心血管  細胞生物  信號轉(zhuǎn)導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PNPLA3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008]

Function:
Multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities.

Subcellular Location:
Membrane; Single pass type II membrane protein.

DISEASE:
Disease susceptibility is associated with variations affecting the gene represented in this entry.
Disease description:A condition characterized by accumulation of triglycerides in the liver. It is associated with adverse metabolic consequences, including insulin resistance and dyslipidemia. In a subset of individuals, hepatic steatosis promotes an inflammatory response in the liver, referred to as steatohepatitis, which can progress to cirrhosis and liver cancer. NAFLD is the most common form of liver disease in Western countries.

Similarity:
Contains 1 patatin domain.

Database links:

Entrez Gene: 609368 Dog

Entrez Gene: 101131854 Gorilla

Entrez Gene: 101824852 Hamster

Entrez Gene: 80339 Human

Entrez Gene: 100406659 Marmoset (common)

Entrez Gene: 116939 Mouse

Entrez Gene: 100344884 Rabbit

Entrez Gene: 362972 Rat

Omim: 609567 Human

SwissProt: Q9NST1 Human

SwissProt: Q91WW7 Mouse

Unigene: 654800 Human

Unigene: 390817 Mouse

Unigene: 97779 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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