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Rabbit Anti-phospho-Thymidine Kinase 1 (Ser13)/AP Conjugated antibody (bs-19666R-AP)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19666R-AP
英文名稱1 Rabbit Anti-phospho-Thymidine Kinase 1 (Ser13)/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的磷酸化胸苷激酶1抗體
別    名 Thymidine Kinase 1 (phospho S13); p-Thymidine Kinase 1 (phospho S13); cytosolic; KITH_HUMAN; Thymidine kinase 1; Thymidine kinase 1 soluble; Thymidine kinase 1 soluble isoform; Thymidine kinase; Thymidine kinase cytosolic; TK 1; TK 2; TK1; Tk1a; Tk1b; TK2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 細胞生物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Dog, Pig, Hamster, )
產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Thymidine Kinase 1 around the phosphorylation site of Ser13
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. Because of this, Thymidine Kinase can be used as a proliferation marker in the diagnosis, treatment, and follow-up of malignant diseases, especially hematological malignancies. Thymidine Kinase may be observed as a monomer, dimer, trimer or tetramer.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Phosphorylated on Ser-13 in mitosis.

Similarity:
Belongs to the thymidine kinase family.

Database links:

Entrez Gene: 7083 Human

Entrez Gene: 21877 Mouse

Entrez Gene: 24834 Rat

Omim: 188300 Human

SwissProt: P04183 Human

SwissProt: P04184 Mouse

SwissProt: P27158 Rat

Unigene: 515122 Human

Unigene: 2661 Mouse

Unigene: 195325 Rat

Unigene: 216486 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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