| 產(chǎn)品編號 | bs-18168R-BF594 |
| 英文名稱1 | Rabbit Anti-Tollip/BF594 Conjugated antibody |
| 中文名稱 | BF594標(biāo)記的Toll蛋白相互作用蛋白抗體 |
| 別 名 | Adapter protein; FLJ33531; IL 1RAcPIP; IL1RAcPIP; TOLIP; TOLIP_HUMAN; Toll interacting protein; Toll-interacting protein; tollip. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Xenopus laevis) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 30kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Tollip |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. [provided by RefSeq, Aug 2011] Function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Subcellular Location: Cytoplasm. Post-translational modifications: Phosphorylated by IRAK1 upon stimulation by IL-1 or microbial products. Similarity: Belongs to the tollip family. Contains 1 C2 domain. Contains 1 CUE domain. Database links: Entrez Gene: 54472 Human Entrez Gene: 423099 Chicken Entrez Gene: 54473 Mouse Entrez Gene: 336876 Zebrafish Omim: 606277 Human SwissProt: Q5ZK05 Chicken SwissProt: Q9H0E2 Human SwissProt: Q9QZ06 Mouse SwissProt: Q7ZV43 Zebrafish Unigene: 368527 Human Unigene: 103551 Mouse Unigene: 137040 Rat Unigene: 79855 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
