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Rabbit Anti-srGAP3/Gold Conjugated antibody (bs-3660R-Gold)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-3660R-Gold
英文名稱 Rabbit Anti-srGAP3/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的精神障礙相關(guān)GAP蛋白抗體
別    名 ARHGAP 14; ARHGAP14; Gbi; ME GAP; MEGAP; Mental disorder associated GAP; Rho GTPase activating protein 14; SLIT ROBO Rho GTPase activating protein 3; srGAP 2; srGAP 3; srGAP2; SRGP 2; SRGP2; WAVE associated Rac GTPase activating protein; WRP.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  激酶和磷酸酶  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 121kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human srGAP3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
srGAP3 (SLIT ROBO Rho GTPase-activating protein 3) is a GTPase activating protein (GAP) for the small G protein Rac. It has a putative role in attenuating Rac1 signalling in neurons. srGAP3 is thought to act downstream of the Slit-Robo pathway, which regulates neuronal migration and axonal branching, and play an important role in axonal regeneration after axotomy. It also plays a putative role in severe mental retardation.

Subunit:
Interacts with WASF1. Probably interacts with ROBO1. Interacts with FASLG.

Tissue Specificity:
Highly expressed in adult and fetal brain. Expressed at low levels in kidney. Isoform 3 is expressed in the kidney but is absent in the brain.

Database links:

Entrez Gene: 9901 Human

Entrez Gene: 259302 Mouse

Entrez Gene: 500287 Rat

Omim: 606525 Human

SwissProt: O43295 Human

SwissProt: Q812A2 Mouse

Unigene: 654743 Human

Unigene: 236401 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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