mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
在线观看99精品视频,AV成人午夜无码一区二区
Rabbit Anti-Zic2/Cy5.5 Conjugated antibody (bs-11610R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11610R-Cy5.5
英文名稱1 Rabbit Anti-Zic2/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的鋅指蛋白Zic2抗體
別    名 HPE 5; HPE5; Odd paired homolog Drosophila; Zic 2; Zic family member 2 (odd paired Drosophila homolog); Zic family member 2; ZIC2; ZIC2_HUMAN; Zinc finger protein of the cerebellum 2; Zinc finger protein ZIC 2; Zinc finger protein Zic2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Zic2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2008]

Function:
Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.

Subcellular Location:
Nucleus. Cytoplasm. Localizes in the cytoplasm in presence of MDFIC overexpression. Both phosphorylated and unphosphorylated forms are localized in the nucleus.

Post-translational modifications:
Phosphorylated.
Ubiquitinated by RNF180, leading to its degradation.

DISEASE:
Defects in ZIC2 are a cause of holoprosencephaly type 5 (HPE5) [MIM:609637]. A structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability. Although severe facial anomalies are common in HPE, patients with ZINC2 mutations have relatively normal faces.

Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.

Database links:

Entrez Gene: 7546 Human

Entrez Gene: 22772 Mouse

Entrez Gene: 361096 Rat

Omim: 603073 Human

SwissProt: O95409 Human

SwissProt: Q62520 Mouse

Unigene: 653700 Human

Unigene: 308936 Mouse

Unigene: 64359 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
在线一区欧美日韩国产| 日韩欧美亚洲精品成人| 中文人妻精品一区在线| 日本一区二区三区综合| 美女久久久高潮喷水91| 国产国语对白在线观看| 欧美精品精品一区乱| 久久国产成人高清精品亚洲| 欧美色到久久88综合亚洲精品| 99久久免费精品国产免费高清| 亚洲线日本一区二区三区| 亚洲精品成人在线播放| 亚洲国产精品午夜福利久久| 亚洲天堂网2020| 欧美日韩一区二区三区大片在线观看| 欧美日韩一区二区中文字幕| 亚洲欧美国产中文字幕91在线| 欧美乱码精品一区二区三区卡| 亚洲欧美日韩一区二区搜索| 久久久久久久久久久极品| 国产三级网络视频在线观看| 精品日韩一区二区电影| 亚洲hhh视频在线看| 乱子伦一区二区三区| 国产精品久久久久粉嫩小| 国产精品一区二区三区三级天堂| 久久久久久亚洲一区二区| 白嫩丰满少妇一区二区| 日本精品最新字幕一区二区| 久久亚洲精品国产av| 欧美激情国产精品视频| 中文亚洲欧美日韩国产| 亚洲永久精品国产来久精品| 欧美中文亚洲国产日韩| 日本无人区一区二区三区| 国产综合精品久久久久成人蜜臀| 中文字幕日韩在线高清欧美| 亚洲男人天堂成人网| 欧美精品在欧美一区二区三区| 国产一级r片内射老熟女| 欧美一级精品片在线看|