mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
999久久久一区二区三区视频,三级全黄加日本天天黄
Rabbit Anti-ERC1/PE-Cy3 Conjugated antibody (bs-11344R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11344R-PE-Cy3
英文名稱 Rabbit Anti-ERC1/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的RAB6蛋白抗體
別    名 Cast 2; CAST2; CAZ-associated structural protein 2; Elks; ELKS/RAB6 interacting/CAST family member 1; ERC 1; ERC protein 1; ERC1 protein; KIAA1081; MGC12974; RAB6 interacting protein 2; RAB6IP2; RB6I2_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 128kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ERC1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 ∑C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20∑C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ∑C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. The protein is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Five transcript variants encoding different isoforms have been found for this gene.

Subunit:
Part of a complex with CHUK, IKBKB and IKBKG. Interacts with CHUK, IKBKB and IKBKG. The interaction with IKBKG is independent of CHUK and IKBKB. Interacts with NFKBIA. Isoform 4 interacts with PPFIA1, and through its C-terminus with the PDZ domains of RIMS1 and RIMS2. Interacts with ERC2/CAST1. Interacts with the GTB-bound forms of RAB6A isoform 1 and isoform 2 and with RAB6B. The interaction was strongest with RAB6B, followed by RAB6A isoform 2 and weakest with RAB6A isoform 1 (By similarity).

Subcellular Location:
Cytoplasmic. Membrane; peripheral membrane protein. Golgi apparatus; Golgi apparatus membrane; peripheral membrane protein.

Tissue Specificity:
Widely expressed. Isoform 2 and isoform 4 are abundantly expressed in brain. Isoform 1 and isoform 3 are predominantly expressed in testis and thyroid, and isoform 1 predominates in other tissues tested.

DISEASE:
Defects in ERC1 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving ERC1/RAB6IP2 is found in cause of thyroid papillary carcinomas. Translocation t(10;12)(q11;p13) involving RET. In vitro, isoform 1, isoform 3 and isoform 5 participating in a ERC1-RET fusion protein activate tyrosine-protein kinase activity.

Similarity:
Contains 1 FIP-RBD domain.

Database links:

Entrez Gene: 23085 Human

Entrez Gene: 111173 Mouse

Entrez Gene: 266806 Rat

Omim: 607127 Human

SwissProt: Q8IUD2 Human

SwissProt: Q99MI1 Mouse

SwissProt: Q811U3 Rat

Unigene: 601216 Human

Unigene: 288860 Mouse

Unigene: 446801 Mouse

Unigene: 207836 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
尤物AV无码国产在线看| 99国产精品一区二区| 欧美大鸡巴捅骚逼吃| 亚洲天堂成年人在线视频| 国产午夜爽爽爽男女免费动漫AV| 国产 自拍 欧美 在线| 国产精品一区二区在线观看91| 大鸡扒干美女BB直流水| 天天摸天天添人人澡| 小骚货舔小骚逼视频| 美女日比视频播放| 亚洲欧美日韩另类| 国产老妇伦国产熟女91| 男人的下面进女人的下面在线观看| 午夜性福福利视频一区二区三区| 最新免费高清无码片| 久久精品国产自清天天线| 9国产亚洲精品国产| 好爽轻点太大了太深了视频| 久久久久精品无码专区喝奶| 久久久久久国产A免费观看| 久久无码免费视频| 男人吃奶大鸡巴操逼视频| 亚洲精品国产综合一线久久| 被大鸡巴操淫液视频| 欧美亚洲另类天天综合网| 美女被插b在线观看| 被大鸡巴操淫液视频| 亚洲精品一区二区精华液| 黄色高清带三级1集2集| 日韩久久奶茶视频| 国产一区二区三区在线观| 久久国产老熟女老女人| 亚洲国产一区二区不卡在线资源| 国产精品无码一二区免费| 亚洲日韩不卡一区二区三区| 精品人妻少妇一区二区三区不卡| 搞段B片黄色全免费看看| 日韩人妻无码中字一区二区| 成人国产亚洲精品一区二| 非洲大鸡巴操逼黄色录像|