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Mouse Anti-PSA (PA5)/PE-Cy7 Conjugated antibody (bsm-1626M-PE-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bsm-1626M-PE-Cy7
英文名稱 Mouse Anti-PSA (PA5)/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的鼠抗人前列腺特異性抗原單克隆抗體(檢測)
別    名 antigen, prostate-specific; APS; Gamma seminoprotein; Gamma-seminoprotein; hK3; Kallikrein 3; Kallikrein 3, (prostate specific antigen); Kallikrein related peptidase 3; Kallikrein-3; KLK 3; KLK2A1; KLK3; KLK3_HUMAN; P 30 antigen; P-30 antigen; P30 antigen; Prostate Specific Antigen; Prostate-specific antigen; PSA; Semenogelase; Seminin.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 PA5
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Full length native protein purified from human
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Function:
Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Subunit:
Forms heterodimer with SERPINA5.

Subcellular Location:
Secreted.

Tissue Specificity:
Prostate.

Similarity:
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.

Database links:

Entrez Gene: 354 Human

Omim: 176820 Human

SwissProt: P07288 Human

Unigene: 171995 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PSA-前列腺特異性抗原為激肽釋放酶家族蛋白,為絲氨酸蛋白酶,由前列腺上皮產(chǎn)生,精液中的濃度很高,可使精液凝塊水解、液化,功能與男性生育力有關(guān).
此抗體可用于試劑盒檢測用抗體。
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