產(chǎn)品編號(hào) | bs-20539R |
英文名稱 | Rabbit Anti-ELP3 antibody |
中文名稱 | 組蛋白乙酰轉(zhuǎn)移酶KAT9抗體 |
別 名 | ELP3_HUMAN; Elongator complex protein 3; EC:2.3.1.-; hELP3; tRNA uridine(34) acetyltransferase; elongator acetyltransferase complex subunit 3; KAT9; |
Specific References (1) | bs-20539R has been referenced in 1 publications.
[IF=5.753] Xiaojun Zhang. et al. TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose‐6‐phosphate dehydrogenase (G6PD). 2021 Feb 25 IP ; Human.
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研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Pig,Sheep,Cow,Dog) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 62kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ELP3: 1-100/547 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009] Function: Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity. Subcellular Location: Cytoplasm. Nucleus. Similarity: Belongs to the ELP3 family. Contains 1 N-acetyltransferase domain. SWISS: Q9H9T3 Gene ID: 55140 Database links: Entrez Gene: 55140 Human Entrez Gene: 74195 Mouse SwissProt: Q9H9T3 Human SwissProt: Q9CZX0 Mouse |