| 產(chǎn)品編號 | bs-17791R |
| 英文名稱 | Rabbit Anti-MRPL40 antibody |
| 中文名稱 | 線粒體核糖體蛋白L40抗體 |
| 別 名 | 39S ribosomal protein L40; 39S ribosomal protein L40 mitochondrial; 39S ribosomal protein L40, mitochondrial precursor; FLJ41774; L40mt; MGC9400; mitochondrial; Mitochondrial ribosomal protein L40; MRP 40; MRP L22; MRP-L40; MRP40; MRPL22; MRPL40; NLVCF; Nuclear localization signal containing protein deleted in velocardiofacial syndrome; Nuclear localization signal deleted in velocardiofacial syndrome; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome; RM40_HUMAN; Up-regulated in metastasis; URIM. |
| 研究領(lǐng)域 | 細胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 細胞類型標(biāo)志物 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 19kDa |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MRPL40: 131-206/206 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008] Subcellular Location: Mitochondrion. Tissue Specificity: Ubiquitous. SWISS: Q9NQ50 Gene ID: 64976 Database links: Entrez Gene: 64976 Human Omim: 605089 Human SwissProt: Q9NQ50 Human Unigene: 431307 Human |
