| 產(chǎn)品編號 | bs-17364R |
| 英文名稱 | HOXB7 Rabbit pAb |
| 中文名稱 | 同源盒蛋白B7抗體 |
| 別 名 | AI325018; HHO C1; HHO.C1; homeo box B7; homeo box c1 protein; Homeobox 2C; homeobox B7; Homeobox protein HHO.C1; Homeobox protein Hox-2C; Homeobox protein Hox-B7; Hox 2.3; Hox 2.3, mouse, homolog of; Hox-2.3; HOX2; HOX2C; Hoxb7; HXB7_HUMAN. |
| 研究領域 | 細胞生物 轉錄調節(jié)因子 表觀遺傳學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Sheep,Chicken,Horse) |
| 產(chǎn)品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 24 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HOXB7: 101-200/217 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. A segment of the HoxB7 proximal promoter drives renal expression of reporter genes specifically in the ureteric bud and collecting ducts. Expression levels of HoxB7 are lower in lymph node metastasis-positive cancer tissues than negative cancer tissues. These results suggest that aberrant expression of HOX genes is related to the development of breast cancer and malignant behavior of cancer cells. Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Subcellular Location: Nucleus. Similarity: Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain. SWISS: P09629 Gene ID: 3217 Database links: Entrez Gene: 3217 Human Entrez Gene: 15415 Mouse Omim: 142962 Human SwissProt: P09629 Human SwissProt: P09024 Mouse Unigene: 436181 Human Unigene: 390366 Mouse Unigene: 113631 Rat |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
