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DMRT1 Rabbit pAb (bs-14346R)  
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50ul/1180.00元
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產品編號 bs-14346R
英文名稱 DMRT1 Rabbit pAb
中文名稱 DMRT1蛋白抗體
別    名 DM domain expressed in testis 1; DM domain expressed in testis protein 1; DMRT 1; dmrt1; DMRT1_HUMAN; DMT 1; DMT1; Doublesex and mab 3 related transcription factor 1; Doublesex-and mab-3-related transcription factor 1.  
Specific References  (1)     |     bs-14346R has been referenced in 1 publications.
[IF=8.025] Chang Shu. et al. Function of Foxl2 and Dmrt1 proteins during gonadal differentiation in the olive flounder Paralichthys olivaceus. INT J BIOL MACROMOL. 2022 Aug;215:141  WB ;  Fish.  
研究領域 細胞生物  轉錄調節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Sheep,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DMRT1: 31-130/373 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]

Function:
May be required for testis development.

Subcellular Location:
Nucleus.

Tissue Specificity:
Testis specific.

Similarity:
Belongs to the DMRT family.
Contains 1 DM DNA-binding domain.

SWISS:
Q9Y5R6

Gene ID:
1761

Database links:

Entrez Gene: 1761 Human

Omim: 602424 Human

SwissProt: Q9Y5R6 Human

Unigene: 98586 Human



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