| 產(chǎn)品編號 | bs-11112R |
| 英文名稱 | Rabbit Anti-PCDH18 antibody |
| 中文名稱 | 原鈣粘附蛋白18抗體 |
| 別 名 | PCD18_HUMAN; PCDH18; PCDH68L; protocadherin 18; protocadherin 68-like protein; Protocadherin-18. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 細(xì)胞外基質(zhì) 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 123kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PCDH18: 381-480/1135 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH18 (protocadherin 18), also known as PCDH68L, is a 1,135 amino acid single-pass type I cell membrane protein that contains six cadherin domains and a cytoplasmic tail that differs from classical cadherins. Expressed ubiquitously with highest expression in ovary and lung, PCDH18 interacts with Dab1 and functions as a potential calcium-dependent adhesion protein that may be involved in the establishment of cell-cell connections in the brain. Multiple isoforms of PCDH18 exist due to alternative splicing events. Function: Potential calcium-dependent cell-adhesion protein. Subcellular Location: Cell membrane. Tissue Specificity: Expressed in all tissues, with highest expression in lung and ovary. Similarity: Contains 6 cadherin domains. SWISS: Q9HCL0 Gene ID: 54510 Database links: Entrez Gene: 54510 Human SwissProt: Q9HCL0 Human |
| 產(chǎn)品圖片 |
Sample: Lovo (human)cell Lysate at 40 ug
Primary: Anti- PCDH18(bs-11112R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 123 kD
Observed band size:123 kD
|
