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Rabbit Anti-ZNF146  antibody (bs-6755R)  
~~~促銷代碼KT202411~~~
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100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-6755R
英文名稱 Rabbit Anti-ZNF146  antibody
中文名稱 鋅指蛋白146抗體
別    名 Only zinc finger protein; OZF; OZF_HUMAN; Zfp146; Zinc finger protein 146; Zinc finger protein OZF; ZNF146; MGC125660; MGC125661.  
研究領域 腫瘤  腫瘤細胞生物標志物  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF146: 121-220/292 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.

Subunit:
Binds DNA. Interacts with SUMO conjugating enzyme UBC9/UBE2I. Interacts with the telomeric protein TERF2IP.

Subcellular Location:
Nucleus.

Tissue Specificity:
Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpressed in 80% of colorectal cancers.

Post-translational modifications:
Sumoylated.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 10 C2H2-type zinc fingers.

SWISS:
Q15072

Gene ID:
7705

Database links:

Entrez Gene: 100138954 Cow

Entrez Gene: 282395 Cow

Entrez Gene: 7705 Human

Entrez Gene: 26465 Mouse

Entrez Gene: 677248 Mouse

Omim: 601505 Human

SwissProt: Q28151 Cow

SwissProt: Q15072 Human

SwissProt: Q8BQN6 Mouse

Unigene: 643436 Human

Unigene: 446516 Mouse

Unigene: 456449 Mouse



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