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Rabbit Anti-GPR15  antibody (bs-3699R)  
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產(chǎn)品編號(hào) bs-3699R
英文名稱 Rabbit Anti-GPR15  antibody
中文名稱 G蛋白偶聯(lián)受體15抗體
別    名 GPCR GPR15; BOB; G protein coupled receptor 15; G protein coupled receptor GPR15; GPR15_HUMAN; G-protein coupled receptor 15; Brother of Bonzo.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  細(xì)胞表面分子  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:200-800,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 40kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR15: 51-150/360 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]

Function:
Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P49685

Gene ID:
2838

Database links:

Entrez Gene: 2838 Human

Entrez Gene: 71223 Mouse

Entrez Gene: 288181 Rat

Omim: 601166 Human

SwissProt: P49685 Human

SwissProt: Q0VDU3 Mouse

Unigene: 563128 Human

Unigene: 359970 Mouse

Unigene: 426544 Mouse



G蛋白偶聯(lián)受體是一種細(xì)胞表面受體,能將細(xì)胞外的分子信號(hào)傳遞至細(xì)胞內(nèi)激起細(xì)胞反應(yīng),對(duì)多種細(xì)胞行起調(diào)控作用。G蛋白偶聯(lián)受體(GPCR)參與了機(jī)體內(nèi)多種生理過程的調(diào)節(jié),是目前治療多種人類疾病包括代謝性疾病的藥物靶點(diǎn)。
產(chǎn)品圖片
Tissue/cell: Mouse stomach tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GPR15 Polyclonal Antibody, Unconjugated(bs-3699R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: rat stomach tissue; Frozen section; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GPR15 Polyclonal Antibody, Unconjugated(bs-3699R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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