| 產(chǎn)品編號(hào) | bs-1671R |
| 英文名稱 | CCR2 + CCR5 Rabbit pAb |
| 中文名稱 | 細(xì)胞表面趨化因子受體2A抗體 |
| 別 名 | CC-CKR-2; C-C Chemokine receptor 2A; C C CKR 2; CC chemokine receptor type 2; CC CKR 2; CCCKR2; CCR 2; CCR1L; CCR2A; CCR2B; CCR5L; CD192; CD192 antigen; Chemokine C C motif receptor 2; Chemokine CC Motif Receptor 2; CKR 2; CKR2; CKR2A; CKR2B; CMKBR2; MCP |
| 研究領(lǐng)域 | 細(xì)胞膜受體 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CCR2 and CCR5: 201-300/373 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]. Function: Receptor for the MCP-1 (JE), MCP-3 (FIC) and MCP-5 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Subunit: Interacts with ARRB1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Detected in monocyte/macrophage cell lines, but not in nonhematopoietic cell lines. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P51683 Gene ID: 12772 Database links: Entrez Gene: 12772 Mouse Entrez Gene: 729230 Human Omim: 601267 Human SwissProt: P41597 Human SwissProt: P51683 Mouse Unigene: 511794 Human Unigene: 705362 Human Unigene: 6272 Mouse Unigene: 211983 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Sp2/0 (Mouse) Cell Lysate at 30 ug
Lane 2: Raw264.7 (Mouse) Cell Lysate at 30 ug
Primary:
Anti-CCR2 + CCR5 (bs-1671R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42-50 kD
Observed band size: 50 kD
|
