| 產(chǎn)品編號 | bs-42423P |
| 英文名稱 | Recombinant Human LGR5 Protein, N-His |
| 中文名稱 | 重組人G蛋白偶聯(lián)受體49蛋白 |
| 別 名 | G protein coupled receptor 49; G-protein coupled receptor 49; G-protein coupled receptor 67; GPCR GPR49; G protein coupled receptor 67; FEX; g protein-coupled receptor fex; G-protein coupled receptor HG38; GPR 49; GPR 67; GPR67; Leucine rich repeat contai |
| 理論分子量 | 28kDa |
| 濃 度 | >2mg/ml |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Lgr5基因（Wnt細(xì)胞信號系統(tǒng)）是一種G蛋白偶聯(lián)受體，已經(jīng)被確定為幾種成年組織和癌癥中干細(xì)胞的一個獨特標(biāo)記。Lgr5最初是在結(jié)腸癌細(xì)胞中發(fā)現(xiàn)的，有報道稱：在惡化前的小鼠腺瘤中也有發(fā)現(xiàn)，這說明Lgr5很可能也是其他組織成體干細(xì)胞和癌癥干細(xì)胞的標(biāo)志物。 |
| 產(chǎn)品圖片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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