| 產(chǎn)品編號 | bs-41245P |
| 英文名稱 | Recombinant human GDF15 protein, N-His |
| 中文名稱 | 重組人生長分化因子15/巨嗜細(xì)胞抑制因子1蛋白 |
| 別 名 | GDF 15; GDF-15; GDF15_HUMAN; Growth differentiation factor 15; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC 1; Mic-1; MIC1; NAG 1; NAG-1; NAG1; NRG 1; NRG-1; NRG1; NSAID (nonsteroidal anti inflammatory drug) activated protein 1; |
| 理論分子量 | 12.7kDa |
| 性 狀 | Liquid |
| 濃 度 | >0.5mg/ml |
| 緩 沖 液 | 20mM Tris-HCL (pH=8.0) with 150mM NaCL |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53. 生長分化因子15（GDF15）是骨形態(tài)發(fā)生蛋白（BMP）和轉(zhuǎn)化生長因子-β超家族成員。GDF-15又叫巨噬細(xì)胞抑制因子（macrophage inhibiting cytokine，MIC）-1、胎盤轉(zhuǎn)化生長因子 （placental transformation growth factor，PTGF）-β、前列腺衍生因子（prostate derived factor，PDF）和胎盤骨形態(tài)發(fā)生蛋白（placental bone morphogeneticprotein，PLAB）。 有學(xué)者認(rèn)為：GDF |
