mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
玖玖资源中文字幕一区二区,欧美日韩国产综合一区二区三区,久久久99国产精品一区
Mouse Anti-Cathepsin D/Cy5 Conjugated antibody (bsm-51237M-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bsm-51237M-Cy5
英文名稱 Mouse Anti-Cathepsin D/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的小鼠抗組織蛋白酶D輕鏈抗體
別    名 Cathepsin D light chain; CatD; CathepsinD; Cathepsin-D; CLN10; CPSD; CTSD; Lysosomal aspartyl peptidase; MGC2311; CATD_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  合成與降解  細(xì)胞粘附分子  細(xì)胞外基質(zhì)  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 7B4
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11/38/45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human Cathepsin D
亞    型 IgG1
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Cathepsin D is a normal lysosomal protease that is expressed in all cells. It is an aspartyl protease with a pH optimum in the range of 3-5, and contains two N-linked oligosaccharides. Cathepsin D is synthesized as an inactive 52 kDa pro enzyme. Activation involves the proteolytic removal of the 43 amino acid profragment and an internal cleavage to generate the two-chain form made up of 34 and 14 kDa subunits. Cathepsin D contains the mannose-6-phosphate lysosomal localization signal that targets the enzyme to the lysosomal compartment where it functions in the normal degradation of proteins. In certain tumor cells, Cathepsin D is abnormally processed and is secreted in its 52 kDa precursor form. Numerous clinical studies as well as in vitro evidence suggest that cathepsin D plays an important role in malignant transformation and may be a useful prognostic indicator for breast cancer and possibly Alzheimer's disease.

Function:
Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Subcellular Location:
Lysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Tissue Specificity:
Expressed in the aorta extrcellular space (at protein level).

Post-translational modifications:
N- and O-glycosylated.

DISEASE:
Defects in CTSD are the cause of neuronal ceroid lipofuscinosis type 10 (CLN10); also known as neuronal ceroid lipofuscinosis due to cathepsin D deficiency. A form of neuronal ceroid lipofuscinosis with onset at birth or early childhood. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material, and clinically by seizures, dementia, visual loss, and/or cerebral atrophy.

Similarity:
Belongs to the peptidase A1 family.

Database links:

Entrez Gene: 1509 Human

Entrez Gene: 13033 Mouse

Omim: 116840 Human

SwissProt: P07339 Human

SwissProt: P18242 Mouse

Unigene: 654447 Human

Unigene: 231395 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久一区二区三区精华液介绍| 韩国无玛黄片毛片| 一区二区国产欧美日韩无| 啊服慢一点插入逼逼| 午夜国产三级一区二区三| 国产欧美一区二区精品久久久| 大鸡吧干小逼逼视频大全| 成人刺激性视频在线观看| 操美女逼逼色逼网| 最新日本一区二区三区免费看| 99久久九九爱精品国产| 日韩美女一区二区三区香蕉视频| 国产亚洲欧美中文日韩| 束缚久久久久久免费高潮| 国产裸模大尺度私拍视频| 男人草女人的视频免费看| 无码一区二区三区色哟哟| 欧美一区二区三区高清性群p| 亚洲国产成人手机版| 91性潮久久久久久久久| 高颜值情侣鸡巴插插淫叫| 亚洲欧美中文字幕第二十| 中文字幕在线观一二三区| 被几个大屌老外轮操| 天堂丝袜人妻中文字幕在线| 欧美日韩在线成人| 男男大鸡巴操小屁眼视频| 在线观看日韩欧美| 国产午夜爽爽爽男女免费动漫AV| 为什么搜索不到裸体| 美女逼男逼小穴小骚下载| 白嫩在线亚洲观看| 国产成人AV剧情| 美女被插入小穴涩涩视频| 伊人网在线免费视频| 男人天堂av在线免费看| 一级特黄大片色欧美精品| 91久国产在线观看| 女人18片毛片。| 欧美人人做人人爽人人喊| 亚洲精品精品精国产|