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Rabbit Anti-RBM42/Biotin Conjugated antibody (bs-21296R-Bio)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-21296R-Bio
英文名稱 Rabbit Anti-RBM42/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的RNA結(jié)合蛋白42抗體
別    名 MGC10433; RNA binding motif protein 42; RNA binding protein 42.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBM42
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
RNA binding motif protein 42 (RBM42) C-terminal domain interacts with HNRNPK C-terminla domain and RNA. RBM42 and HNRNPK are involved in the maintenance of cellular ATP levels during stress, possibly by protecting critical mRNAs. Upon stress response, RBM42 localizes with HNRNPK in cytoplasmic aggregates of stalled translational pre-initiation complexes called stress granules. There are 4 isoforms produced by alternative splicing.

Function:
Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.

Subunit:
Interacts with HNRNPK.

Subcellular Location:
Cytoplasmic and Nuclear.

Similarity:
Belongs to the RRM RBM42 family.
Contains 1 RRM (RNA recognition motif) domain.

Database links:

Entrez Gene: 79171 Human

Entrez Gene: 68035 Mouse

Entrez Gene: 361545 Rat

GenBank: NP_077297.2 Human

Omim: 613232 Human

SwissProt: Q9BTD8 Human

SwissProt: Q91V81 Mouse

SwissProt: Q6AXT7 Rat

Unigene: 5086 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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