| 產(chǎn)品編號(hào) | bs-20154R-BF350 |
| 英文名稱1 | Rabbit Anti-PCDH7/BF350 Conjugated antibody |
| 中文名稱 | BF350標(biāo)記的原鈣粘蛋白7抗體 |
| 別 名 | BH Pcdh; BH protocadherin; BH-Pcdh; BHPCDH; Brain heart protocadherin; Brain-heart protocadherin; PCDH 7; PCDH7; PCDH-7; PCDH7_HUMAN; Protocadherin 7; Protocadherin7; Protocadherin-7. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 細(xì)胞分化 細(xì)胞骨架 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Mouse, Rat, Pig, Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 113kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PCDH7 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: As a subfamily of the cadherin superfamily, protocadherins are cadherin-like cell adhesion proteins that contain up to seven extracellular domains and are predominantly expressed in the nervous system. Importantly, the adhesion mechanism of protocadherins is distinct from classic cadherins. Through inactivation or overexpression, several protocadherins have been implicated in a variety of cancers. PCDH7 (protocadherin 7), also known as BHPCDH or BH-Pcdh, is a 1069 amino acid single-pass I membrane protein that is expressed in the brain and heart. Containing seven cadherin domains, PCDH7 is thought to function in cell-cell recognition and adhesion. PCDH7 exists as three isoforms due to alternative splicing events. Function: Expressed predominantly in brain and heart and at lower levels in various other tissues. Subcellular Location: Cell membrane. Post-translational modifications: Isoform C is phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 7 cadherin domains. Database links: Entrez Gene: 5099 Human Entrez Gene: 54216 Mouse Omim: 602988 Human SwissProt: O60245 Human Unigene: 479439 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
