| 產(chǎn)品編號(hào) | bs-12632R-Gold |
| 英文名稱(chēng) | Rabbit Anti- PFKFB4/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標(biāo)記的果糖-2,6-二磷酸酶4抗體 |
| 別 名 | 6-bisphosphatase; 6-P2ase 4; 6-P2ASE testis-type isozyme; 6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4; 6PF 2 K/Fru 2,6 P2ase 4; 6PF 2 K/Fru 2,6 P2ase testis type isozyme; 6PF-2-K/Fru-2; 6PF-2-K/Fru-2,6-P2ase; Bifunctional enzyme with kinase and biphosphatase activities; F264_HUMAN; Fructose-2; Fructose-2,6-bisphosphatase; PFK/FBPase 4; PFKFB4. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PFKFB4 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] Function: Synthesis and degradation of fructose 2,6-bisphosphate. Subunit: Homodimer. Similarity: In the C-terminal section; belongs to the phosphoglycerate mutase family. Database links: Entrez Gene: 5210 Human Entrez Gene: 270198 Mouse Omim: 605320 Human SwissProt: Q16877 Human SwissProt: Q6DTY7 Mouse Unigene: 476217 Human Unigene: 249861 Mouse Unigene: 90092 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
