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Rabbit Anti-SEC61A/BF350 Conjugated antibody (bs-19618R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19618R-BF350
英文名稱1 Rabbit Anti-SEC61A/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的轉(zhuǎn)運(yùn)蛋白SEC61A抗體
別    名 chunp6898; fb62c11; HSEC61; protein transport protein SEC61 alpha subunit; protein transport protein Sec61 subunit alpha; Protein transport protein Sec61 subunit alpha isoform 1; S61A1_HUMAN; SEC 61; SEC 61A; Sec61 alpha 1; Sec61 alpha 1 subunit; Sec61 alpha 1 subunit (S. cerevisiae); Sec61 alpha-1; SEC61; Sec61 homolog; SEC61A1; sec61aa.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Dog, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEC61A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]

Function:
Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.

Subunit:
Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma.

Subcellular Location:
Endoplasmic reticulum membrane.

Similarity:
Belongs to the secY/SEC61-alpha family.

Database links:

Entrez Gene: 29927 Human

Entrez Gene: 505064 Cow

Entrez Gene: 404006 Dog

Entrez Gene: 53421 Mouse

Entrez Gene: 80843 Rat

Entrez Gene: 192298 Zebrafish

Omim: 609213 Human

SwissProt: Q5EA68 Cow

SwissProt: P38377 Dog

SwissProt: P61619 Human

SwissProt: P61620 Mouse

SwissProt: P61621 Rat

SwissProt: Q90ZM2 Zebrafish

Unigene: 518236 Human

Unigene: 28375 Mouse

Unigene: 485032 Mouse

Unigene: 47029 Rat

Unigene: 51503 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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