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Rabbit Anti-GALNTL5/Gold Conjugated antibody (bs-16228R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16228R-Gold
英文名稱 Rabbit Anti-GALNTL5/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的GalNAc-TL5蛋白抗體
別    名 GalNAc-T15; GALNACT19; GALNT15; GALNTL5; GLTL5_HUMAN; Polypeptide GalNAc transferase 15; pp-GaNTase 15; Protein-UDP acetylgalactosaminyltransferase 15; Putative polypeptide N-acetylgalactosaminyltransferase-like protein 5; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 15; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  細(xì)胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GALNTL5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
GalNAc-TL4 utilizes manganese and calcium as cofactors and is expressed in testis. GalNAc-TL5 may assist with the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on protein receptors and likely catalyzes the initial reaction in O-linked oligosaccharide biosynthesis. Unlike other members of the GalNAc-T subfamily, GalNAc-TL5 does not contain a C-terminal ricin B-type lectin domain. GalNAc-TL5 contains two conserved domains located in its glycosyltransferase region. The N-terminal domain, also known as domain A or GT1 motif, may be involved in manganese coordination and substrate binding while the C-terminal domain, also known as domain B or Gal/GalNAc-T motif, is likely involved in catalytic reactions and UDP-Gal binding. GalNAc-TL5 exists as two alternatively spliced isoforms.

Function:
May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Expressed in testis.

Similarity:
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.

Database links:

Entrez Gene: 168391 Human

Omim: 615133 Human

SwissProt: Q7Z4T8 Human

Unigene: 647077 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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