| 產(chǎn)品編號 |
bs-16223R-BF488 |
| 英文名稱 |
Rabbit Anti-GALNT7/BF488 Conjugated antibody
|
| 中文名稱 |
BF488標(biāo)記的GalNAc-T7蛋白抗體 |
| 別 名 |
GalNAc T7;
GalNAc-T7;
GalNAcT7;
GALNT 7;
Galnt7;
GALT7_HUMAN;
N acetylgalactosaminyltransferase 7;
N-acetylgalactosaminyltransferase 7;
Polypeptide GalNAc transferase 7;
Polypeptide N acetylgalactosaminyltransferase 7;
pp GaNTase 7;
pp-GaNTase 7;
Protein UDP acetylgalactosaminyltransferase 7;
Protein-UDP acetylgalactosaminyltransferase 7;
UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 7;
UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 7;
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 研究領(lǐng)域 |
細胞生物 免疫學(xué) 跨膜蛋白 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, )
|
| 產(chǎn)品應(yīng)用 |
ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
75kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human GALNT7 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation. [provided by RefSeq, Jul 2008]
Function:
Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
Subcellular Location:
Golgi apparatus membrane.
Tissue Specificity:
Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.
Similarity:
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Contains 1 ricin B-type lectin domain.
Database links:
Entrez Gene: 51809 Human
Entrez Gene: 108150 Mouse
Entrez Gene: 100171466 Orangutan
Entrez Gene: 29750 Rat
Omim: 605005 Human
SwissProt: Q86SF2 Human
SwissProt: Q80VA0 Mouse
SwissProt: Q5RFJ6 Orangutan
SwissProt: Q9R0C5 Rat
Unigene: 548088 Human
Unigene: 62886 Mouse
Unigene: 207200 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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