| 產(chǎn)品編號(hào) |
bs-16865R-Cy7 |
| 英文名稱(chēng) |
Rabbit Anti-Kv1.2/Cy7 Conjugated antibody
|
| 中文名稱(chēng) |
Cy7標(biāo)記的電壓門(mén)控鉀通道Kv1.2抗體 |
| 別 名 |
Akr6a4;
BK2;
HBK5;
HK4;
HUKIV;
Kca1 2;
kcna2;
KV1.2;
MGC50217;
Mk 2;
MK2;
NGK1;
Potassium voltage gated channel shaker related subfamily member 2;
Potassium voltage-gated channel subfamily A member 2;
RBK2;
Voltage gated potassium channel subunit Kv1.2.
KCNA2_HUMAN |
| 規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) |
100ul
|
| 研究領(lǐng)域 |
心血管 細(xì)胞生物 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜蛋白 |
| 抗體來(lái)源 |
Rabbit |
| 克隆類(lèi)型 |
Polyclonal |
| 交叉反應(yīng) |
Mouse,
(predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
|
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
57kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human Kv1.2 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
Kv1.2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
Function:
Mediates the voltage-dependent potassium ion
permeability of excitable membranes. Assuming opened or closed
conformations in response to the voltage difference across the
membrane, the protein forms a potassium-selective channel through
which potassium ions may pass in accordance with their
electrochemical gradient.
Subunit:
Heterotetramer of potassium channel proteins.
Subcellular Location:
Membrane; Multi-pass membrane protein
Similarity:
Belongs to the potassium channel family.
Database links:
Entrez Gene: 395117 Chicken
Entrez Gene: 3737 Human
Entrez Gene: 16490 Mouse
Entrez Gene: 25468 Rat
Omim: 176262 Human
SwissProt: P16389 Human
SwissProt: P63141 Mouse
SwissProt: P63142 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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