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Rabbit Anti-EFHA2/BF647 Conjugated antibody (bs-14518R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-14518R-BF647
英文名稱 Rabbit Anti-EFHA2/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的EFHA2蛋白抗體
別    名 EF-HA2; 2900075B16Rik; DKFZp313A0139; EF hand domain family A2; EF hand domain family member A2; EF-hand domain-containing family member A2; Efha2; MICU3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EFHA2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HB (EF-hand domain-containing family member B) is a 831 amino acid protein that contains two EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. There are three isoforms of EF-HB that are produced as a result of alternative splicing events. The gene encoding EF-HB is located on human chromosome three,which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Other well-studied calcium binding proteins that contain EF-hand motifs include calmodulin (CaM), Troponin C, myosin regulatory light chain (MYL) and S-100 proteins

Function:
May play a role in mitochondrial calcium uptake (By similarity).

Subcellular Location:
Mitochondrion (By similarity). Membrane; Single-pass membrane protein (Potential).

Similarity:
Contains 2 EF-hand domains.

Database links:

Entrez Gene: 151651 Human

SwissProt: Q8N7U6 Human

Unigene: 120196 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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