mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
无码囯产精品一区二区免费,国产精品99久久久久久粉嫩,影音先亚洲一区二区锋资源
Rabbit Anti-TRPV5/Cy3 Conjugated antibody (bs-8534R-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@m.p2b3.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-8534R-Cy3
英文名稱(chēng) Rabbit Anti-TRPV5/Cy3 Conjugated antibody
中文名稱(chēng) Cy3標(biāo)記的辣椒素受體5抗體
別    名 Calcium transport protein 2; Calcium transporter 2; CAT 2; CAT2; ECAC 1; ECaC; ECAC1; Epithelial calcium channel 1; Osm 9 like TRP channel 3; Osm-9-like TRP channel 3; OTRPC 3; OTRPC3; Transient receptor potential cation channel subfamily V member 5; TRPV 5; TrpV5; TRPV5_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  通道蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRPV5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Transient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, the thermal-sensitive, capsaicin-insensitive TRPV3 is expressed at warm temperatures; expression increases in response to noxious temperatures. Human TRPV3 is expressed in skin, tongue, dorsal root ganglion, trigeminal ganglion, spinal cord and brain. In addition, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1. TRPV3 associates with VR-1 and may modulate VR-1 activity. The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, multiple potential phosphorylation sites, an N-linked glycosylation site and three ankyrin repeat regions. It is abundantly expressed in kidney, jejunum and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum. TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine; the 5’-flanking region of TRPV5 contains four putative vitamin D3-responsive elements.

Function:
Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Subunit:
Homotetramer and probably heterotetramer with TRPV6. Interacts with TRPV6. Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with calmodulin. Interacts with BSPRY, which results in its inactivation (By similarity).

Subcellular Location:
Apical cell membrane. Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity). The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3.

Tissue Specificity:
Expressed at high levels in kidney, small intestine and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.
Contains 5 ANK repeats.

Database links:

Entrez Gene: 56302 Human

Entrez Gene: 194352 Mouse

Entrez Gene: 116469 Rat

Omim: 606679 Human

SwissProt: Q9NQA5 Human

SwissProt: P69744 Mouse

SwissProt: Q9JIP0 Rat

Unigene: 283369 Human

Unigene: 135734 Mouse

Unigene: 137513 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
爽妇网国产精品24| 色男人天堂亚洲男人天堂| 天天舔操操操av| 中文字幕日韩亚洲| 骚穴 操我 视频| 护士毛片在线看中文字幕| 东京热无码AV一区二区三区| 中文字幕一区二区 在线| 日韩人妻无码中字一区二区| 黄色录像片操大逼的| 日韩av午夜福利在线观看| 男生狂操女生污视频| 日韩激情精品久久久一区二区| 国产乱理伦片在线观看夜| 91久久高清国语自产拍| 国产一二三四五自产| 交换夫妇4中文字幕| 大鸡巴操大屁股美女视频| 国产成人精品免费视频全| 狠狠五月激情综合去干网| 女教师色色天天免费播放| 欧美一区亚洲一区视频在线观看| 大粗鳮巴r教师人妻91| 热精品韩国毛久久久久久| 精品久久久久久不卡亚洲| 一色道久久88加勒比一| 老司机精品免费在线视频| 免费看看小骚逼逼| 国产精品一区二区三区在线视| 亚洲国产精品伦理在线看| 欧美日韩一级视频| 天天躁久久躁中文字字幕| 天天舔操操操av| 强奷很舒服好爽好爽| 亚洲欧洲精品无码久久久| aaa啊啊啊黄片| 操老女人大逼视频| 午夜性福福利视频一区二区三区| 欧美高清一二三区| 无码人妻丰满熟妇区精品| 精品精品视频国产|