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Rabbit Anti-HAPLN4/APC Conjugated antibody (bs-15412R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-15412R-APC
英文名稱1 Rabbit Anti-HAPLN4/APC Conjugated antibody
中文名稱 APC標記的透明質酸及粘蛋白4抗體
別    名 Brain link protein 2; BRAL 2; BRAL2; HAPLN 4; Hapln4; HPLN4_HUMAN; Hyaluronan and proteoglycan link protein 4; Hyaluronan and proteoglycan link protein 4 precursor; KIAA1926.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 信號轉導  細菌及病毒  細胞外基質  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HAPLN4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
HAPLN4 is a 360 amino acid protein encoded by the human gene HAPLN4. HAPLN4 belongs to the HAPLN family and contains 1 Ig-like C2-type (immunoglobulin-like) domain and two Link domains. HAPLN4 mediates the binding of complexes containing hyaluronic acid. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN4 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN4 may also be involved in the formation of extracellular matrices contributing to perineuronal nets and facilitate the understanding of a functional role of these extracellular matrices. HAPLN4 is widely expressed with highest levels in spleen and placenta.

Function:
Binds to hyaluronic acid and may be involved in formation of the extracellular matrix (By similarity).

Subcellular Location:
Secreted, extracellular space, extracellular matrix (By similarity).

Tissue Specificity:
Expressed predominantly in brain.

Similarity:
Belongs to the HAPLN family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 2 Link domains.

Database links:

Entrez Gene: 404037 Human

Entrez Gene: 330790 Mouse

SwissProt: Q86UW8 Human

SwissProt: Q80WM4 Mouse

Unigene: 367829 Human

Unigene: 152048 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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