mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲xx综合好看站芊芊,精品国产av麻豆二区三区
Rabbit Anti-AP2 alpha + beta/HRP Conjugated antibody (bs-12480R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12480R-HRP
英文名稱1 Rabbit Anti-AP2 alpha + beta/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的轉(zhuǎn)錄因子AP2α+β抗體
別    名 Activating enhancer binding protein 2 alpha; Activating enhancer binding protein 2 beta; AP2TF; TFAP2; TFAP2A; TFAP2B; Transcription factor AP2 alpha; Transcription factor AP2 beta; AP2A_HUMAN; AP2B_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  發(fā)育生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AP2 alpha + beta
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer. AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

Function:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

Subunit:
Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I. Interacts with RALBP1 in a complex also containing EPN1 and NUMB during interphase and mitosis. Interacts with KCTD1; this interaction represses transcription activation. Interacts (via C-terminus) with CITED2 (via C-terminus); the interaction stimulates TFAP2A-transcriptional activation. Interacts (via N-terminus) with EP300 (via N-terminus); the interaction requires CITED2.

Subcellular Location:
Nuclear.

Post-translational modifications:
Sumoylated on Lys-10; which inhibits transcriptional activity (Probable).

DISEASE:
Defects in TFAP2A are the cause of branchiooculofacial syndrome (BOFS) [MIM:113620]; also known as branchial clefts with characteristic facies, growth retardation, imperforate nasolacrimal duct, and premature aging or lip pseudocleft-hemangiomatous branchial cyst syndrome. BOFS is a rare autosomal dominant cleft palate craniofacial disorder with variable expressivity. The major features include cutaneous anomalies, ocular anomalies, characteristic facial appearance (malformed pinnae, oral clefts), and, less commonly, renal and ectodermal (dental and hair) anomalies.

Similarity:
Belongs to the AP-2 family.

Database links:
UniProtKB/Swiss-Prot: P05549.1 UniProtKB/Swiss-Prot: Q92481.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
国产日韩欧美久久综合网| 神马午夜久久久久久| 亚洲欧美日韩在线三区| 国产成人三级一区二区在线观看| 日本阿v不卡在线观看视频| 欧美色到久久88综合亚洲精品| 白嫩丰满少妇一区二区| 五月爱婷婷丁香六月色| 99久久成人国产精品| 亚洲欧美成在线观看| 欧美日韩国产成人精品自拍视频| 久久久久成人精品免费播放寂寞少妇| 午夜影院网站免费观看| 亚洲精品电影一区二区三区| 欧美激情a成人综合亚洲综合| 欧美精品精品一区二区三区| 日韩免费码中文字幕在线| 蜜臀99久久精品久久久| 亚洲91精品视频在线观看| 国产精品我不卡尤物| 亚洲国产精品国揄产拍| 亚成区一区二区人妻熟女| 亚洲一道本中文字幕一区二区| 91香蕉在线观看影视| 人人添人人澡五码超碰| 亚洲欧美国产国产第二页| 国产av一区二区三区久久久久| 在线十亚洲十欧美十日本专区| 欧美一级黄片在线播放| 国产精品人成在线观看不卡| 欧美日韩国产成人精品自拍视频| 欧美日韩一区二区三区自拍| 色婷婷久久久久久久久久| 日本边添边摸边做边爱喷水| 草草影院在线免费观看| 国产高新无码在线观看| 国产人成尤物在线免费观看| 亚洲国产成人精品女人久久0| 丰满的大乳老师三级在线观看| 91蜜臀精品一区二区三区| 日产国产精品久久久久久|