| 產(chǎn)品編號 | bs-12193R-BF488 |
| 英文名稱1 | Rabbit Anti-FOXD1/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的叉頭蛋白D1抗體 |
| 別 名 | Brain Factor 2; FKH L8; FKHL 8; FKHL8; Forkhead (Drosophila) like 8; Forkhead box D1; Forkhead box protein D1; Forkhead drosophila homolog like 8; Forkhead like 8; Forkhead related activator 4; Forkhead related protein FKHL8; Forkhead related transcription factor 4; Forkhead-related protein FKHL8; Forkhead-related transcription factor 4; FOX D1; FOXD 1; foxd1; FOXD1_HUMAN; FREAC 4; FREAC-4; FREAC4. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 干細(xì)胞 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞分化 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Chicken, Dog, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 46kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human FOXD1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: FOXD1 is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NFAT and NFkB. Deficiency of FOXD1 results in multiorgan systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation. Function: Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly. Subcellular Location: Nucleus. Similarity: Contains 1 fork-head DNA-binding domain. Database links: Entrez Gene: 2297 Human Entrez Gene: 15229 Mouse GenBank: NP_004463 Human Omim: 601091 Human SwissProt: Q16676 Human SwissProt: Q61345 Mouse Unigene: 519385 Human Unigene: 347441 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
