| 產(chǎn)品編號(hào) | bs-12135R-BF488 |
| 英文名稱 | Rabbit Anti-Striatin 3/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的細(xì)胞周期蛋白SG2N抗體 |
| 別 名 | Striatin3; Striatin-3; Striatin 3; Cell cycle autoantigen SG2NA; Cell cycle S/G2 nuclear autoantigen; GS2NA; nuclear autoantigen; S/G2 antigen; SG2NA; Striatin 3; Striatin, calmodulin binding protein 3; STRN3_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 細(xì)胞膜受體 結(jié)合蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 87kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Striatin 3/SG2NA |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle. Function: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. Subunit: Interacts with protein phosphatase 2A (PP2A) (Potential). Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Similarity: Belongs to the WD repeat striatin family. Contains 6 WD repeats. Database links: Entrez Gene: 29966 Human Entrez Gene: 94186 Mouse SwissProt: Q13033 Human SwissProt: Q9ERG2 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
