mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲日产无码中文字幕在线,国产午夜三级精品久久久
Rabbit Anti-ABCB11/Biotin Conjugated antibody (bs-12440R-Bio)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@m.p2b3.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12440R-Bio
英文名稱1 Rabbit Anti-ABCB11/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的膽汁酸鹽輸出泵/ATP結(jié)合盒轉(zhuǎn)運(yùn)蛋白11抗體
別    名 BSEP; ABC member 16, MDR/TAP subfamily; ABCB1; Abcb11; ABCBB_HUMAN; ATP binding cassette sub family B (MDR/TAP) member 11; ATP binding cassette sub family B member 11; ATP-binding cassette sub-family B member 11; Bile salt export pump; BRIC2; Bsep; PGY4; progressive familial intrahepatic cholestasis 2; Sister of P glycoprotein; Spgp.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Rabbit, )
產(chǎn)品應(yīng)用 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 146kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BSEP/ABCB11
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, Mdr/TAP, MRP, ALD, OABP, GCN20 and White. The secretion of bile salt molecules from blood into bile is a major driving force for bile formation. Bile salt export pump (BSEP) is a member of the Mdr/TAP subfamily of ABC transporters that mediates the transport of bile acids across the hepatocyte canalicular membrane and regulates bile acid-dependent bile secretion. BSEP contains putative phosphorylation sites for protein kinase A, protein kinase C (PKC) and Ca2+-calmodulin dependent kinase II, whose regulation may be dependent on bile salt concentration.

Function:
Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.

Subunit:
Interacts with HAX1.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ.

DISEASE:
Defects in ABCB11 are the cause of progressive familial intrahepatic cholestasis type 2 (PFIC2) [MIM:601847]. PFIC2 is an inherited liver disease of childhood which is characterized by cholestasis and normal serum gamma-glutamyltransferase activity. Defects in ABCB11 are also found in cases of chronic intrahepatic cholestasis without obvious familial history of chronic liver disease.
Defects in ABCB11 are the cause of benign recurrent intrahepatic cholestasis type 2 (BRIC2) [MIM:605479]. BRIC is characterized by intermittent episodes of cholestasis without progression to liver failure. There is initial elevation of serum bile acids, followed by cholestatic jaundice which generally spontaneously resolves after periods of weeks to months. The cholestatic attacks vary in severity and duration and patients are asymptomatic between episodes, both clinically and biochemically.

Similarity:
Belongs to the ABC transporter superfamily. ABCB family.
Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains.

Database links:

Entrez Gene: 8647 Human

Entrez Gene: 27413 Mouse

Entrez Gene: 83569 Rat

Omim: 603201 Human

SwissProt: O95342 Human

SwissProt: Q9QY30 Mouse

SwissProt: O70127 Rat

Unigene: 658439 Human

Unigene: 439855 Mouse

Unigene: 14539 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产精品国产三级av| 国产69精品久久久久久老妇| 欧美日韩国产综合在线视频| 亚洲国产精品无码av| 欧美午夜激情久久久久| 国产日韩欧美老人啪啪| 中文字幕人妻女同一区| 国产精品久久久久久久久三级| 2018在线不卡爱视频| 欧美中文亚洲国产日韩| 亚州在线中文字幕经典a| 日本阿v不卡在线观看视频| 日韩精品高清在线观看| 国产精品久久小视频| 93国产精品久久久久久| 中文字幕视频一区人妻| 在线国产精品一区二区三区| 麻豆理论片在线观看| 丰满少妇爽视频一区二区三区| 国产又粗又长又硬又黄网站| 日韩插久久一区二区三区综合| 一区二区三区久久99精品| 日本色一区二区三区四区五区| 日韩熟女精品一区二区三区| 久久蜜臀亚洲一区二区| 亚洲AV永久无码精品加勒比| 不卡在线视频一区二区| 日本欧美一区二区免费不卡| 色婷婷狠狠久久综合五月| 一区二区三区精品亚洲视频| 国产日韩欧美精品小视频| 91狠狠人妻久久久久久综合| 亚洲国产精品午夜在线| 国产精品久久久久国产三| 久久久精品视频免费在线| 日本伊人久久精品视频| 亚洲国产精品成人一区二区三区| 国产高清国内精品福利免费| 日韩精品久久理论片| 国内精品国产三级国产av万事达| 亚洲综合精品欧美日韩一区二区三区91|