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Rabbit Anti-Mouse serum albumin/APC Conjugated antibody (bs-2256R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-2256R-APC
英文名稱1 Rabbit Anti-Mouse serum albumin/APC Conjugated antibody
中文名稱 APC標(biāo)記的小鼠血清白蛋白抗體
別    名 Alb 1; ALB; ALBU_MOUSE; Albumin 1; Albumin; DKFZp779N1935; PRO0883; PRO0903; PRO1341; PRO2044; PRO2619; Serum albumin.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  發(fā)育生物學(xué)  干細(xì)胞  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 68kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Mouse serum albumin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008].

Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Subcellular Location:
Secreted.

Tissue Specificity:
Plasma.

Post-translational modifications:
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracellular medium.
Acetylated on Lys-223 by acetylsalicylic acid.

DISEASE:
Familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]: Form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains.

Database links:

Entrez Gene: 100379232 Guinea pig

Entrez Gene: 100034206 Horse

Entrez Gene: 213 Human

Entrez Gene: 11657 Mouse

Entrez Gene: 396960 Pig

Entrez Gene: 100009195 Rabbit

Entrez Gene: 24186 Rat

Omim: 103600 Human

SwissProt: P49064 Cat

SwissProt: P19121 Chicken

SwissProt: P02769 Cow

SwissProt: P49822 Dog

SwissProt: P35747 Horse

SwissProt: P02768 Human

SwissProt: P07724 Mouse

SwissProt: P08835 Pig

SwissProt: P49065 Rabbit

SwissProt: P02770 Rat

Unigene: 418167 Human

Unigene: 16773 Mouse

Unigene: 202968 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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