| 產(chǎn)品編號(hào) |
bs-13983R-Gold |
| 英文名稱1 |
Rabbit Anti-COPZ2/Gold Conjugated antibody
|
| 中文名稱 |
膠體金標(biāo)記的衣殼蛋白-ζ2抗體 |
| 別 名 |
Coatomer protein complex, subunit zeta 2;
Coatomer subunit zeta-2;
MGC23008;
Nonclathrin coat protein zeta-COP;
Zeta-2 COP; COPZ2_HUMAN;
Zeta-2-coat protein;
zeta2-COP. |
| 規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 |
100ul（10nm 15nm 35nm）
|
| 研究領(lǐng)域 |
細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 |
| 抗體來(lái)源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, )
|
| 產(chǎn)品應(yīng)用 |
IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
24kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
0.4mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human COPZ2 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 |
Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background:
This gene encodes a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. This gene is similar to a related family member, and the two encoded proteins form distinct isotypes of the coatomer protein complex. [provided by RefSeq, Jul 2008]
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle; COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Database links:
Entrez Gene: 51226 Human
Entrez Gene: 56358 Mouse
SwissProt: Q9P299 Human
SwissProt: Q9JHH9 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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