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Rabbit Anti-Glypican 6/Gold Conjugated antibody (bs-2177R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術支持:techsupport@m.p2b3.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2177R-Gold
英文名稱 Rabbit Anti-Glypican 6/Gold Conjugated antibody
中文名稱 膠體金標記的磷脂酰基醇蛋白聚糖-6抗體
別    名 GPC 6; Glypican6; Glypican-6; Glypican 6 [Precursor]; Glypican proteoglycan 6; GPC 6; GPC6; MGC126288; Secreted glypican 6.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  信號轉導  生長因子和激素  細胞表面分子  細胞骨架  鋅指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Glypican 6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Glypican 6 is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti proteases. The glypicans comprise a family of glycosylphosphatidylinositol anchored heparan sulfate proteoglycans. The glypicans have been implicated in the control of cell growth and division.

Function:
Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted glypican-6: Secreted, extracellular space.

Tissue Specificity:
Widely expressed. High expression in fetal kidney and lung and lower expressions in fetal liver and brain. In adult tissues, very abundant in ovary, high levels also observed in liver, kidney, small intestine and colon. Not detected in peripheral blood leukocytes.

DISEASE:
Defects in GPC6 are a cause of omodysplasia type 1 (OMOD1) [MIM:258315]. OMOD1 is a rare autosomal recessive skeletal dysplasia characterized by severe congenital micromelia with shortening and distal tapering of the humeri and femora to give a club-like appearance. Typical facial features include a prominent forehead, frontal bossing, short nose with a depressed broad bridge, short columella, anteverted nostrils, long philtrum, and small chin.

Similarity:
Belongs to the glypican family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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