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Rabbit Anti-ADAM11/BF488 Conjugated antibody (bs-5846R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5846R-BF488
英文名稱1 Rabbit Anti-ADAM11/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的去整合素樣金屬蛋白酶11抗體
別    名 A disintegrin and metalloproteinase domain 11; ADA11_HUMAN; MDC; Metalloproteinase like, disintegrin like, and cysteine rich protein.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞骨架  細(xì)胞外基質(zhì)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Cow, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ADAM11
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Jul 2008].

Function:
Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein.

Subunit:
Can bind to LGI1 and LGI4.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed predominantly in brain. Slightly detected or not at all in other tissues.

Post-translational modifications:
The precursor is cleaved by a furin endopeptidase.

Similarity:
Contains 1 disintegrin domain.
Contains 1 EGF-like domain.
Contains 1 peptidase M12B domain.

Database links:

Entrez Gene: 4185 Human

Omim: 155120 Human

SwissProt: O75078 Human

Unigene: 6088 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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