| 產(chǎn)品編號 | bs-1272R-BF488 |
| 英文名稱1 | Rabbit Anti-CNTF/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的睫狀神經(jīng)營養(yǎng)因子抗體 |
| 別 名 | Ciliary Neurotrophic Factor; CNTF; CNTF_HUMAN; HCNTF. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 干細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, Rabbit, (predicted: Mouse, Pig, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CNTF (21-70aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition to the predominant monocistronic transcript originating from this locus, the gene is also transcribed as a readthrough transcript with the upstream Zfp91 gene. The resulting protein is an isoform of Zfp91 and does not include Cntf sequence. Readthrough transcription of Zfp91 and Cntf has been observed in human and mouse. Function: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. Subunit: Belongs to the CNTF family. Subcellular Location: Cytoplasm. Tissue Specificity: Nervous system. Similarity: Belongs to the CNTF family. Database links: Entrez Gene: 1270 Human Entrez Gene: 12803 Mouse Omim: 118945 Human SwissProt: P26441 Human SwissProt: Q6NTB0 Human SwissProt: P51642 Mouse Unigene: 524920 Human Unigene: 715806 Human Unigene: 290924 Mouse Unigene: 6067 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 神經(jīng)干細(xì)胞標(biāo)志物 有學(xué)者認(rèn)為：睫狀神經(jīng)營養(yǎng)因子能促進(jìn)運動神經(jīng)軸突再生，CNTF可以阻止損傷后的運動神經(jīng)元的退形性變性，目前CNTF對神經(jīng)營養(yǎng)作用還在深入的研究中。 |
