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Rabbit Anti-SGPL1/FITC Conjugated antibody (bs-4188R-FITC)
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產(chǎn)品編號(hào) bs-4188R-FITC
英文名稱1 Rabbit Anti-SGPL1/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的磷酸鞘氨醇裂解酶1抗體
別    名 FLJ13811; hSPL; KIAA1252; S1P; S1PL; SGPL 1; SGPL1; SGPL1_HUMAN; SP lyase; SP-lyase 1; Sphingosine 1 phosphate aldolase; Sphingosine 1 phosphate lyase 1; Sphingosine-1-phosphate aldolase; Sphingosine-1-phosphate lyase 1; SPL 1; SPL.  
規(guī)格價(jià)格 50ug/1680元 購(gòu)買    100ug/2980元 購(gòu)買    大包裝/詢價(jià)
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研究領(lǐng)域 腫瘤  心血管  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  脂蛋白  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 Flow-Cyt=1ug/Test IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SGPL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.

Function:
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type III membrane protein.

Tissue Specificity:
Found in liver and kidney.

Similarity:
Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.

Database links:

Entrez Gene: 8879 Human

Entrez Gene: 20397 Mouse

Entrez Gene: 286896 Rat

SwissProt: O95470 Human

SwissProt: Q8R0X7 Mouse

SwissProt: Q8CHN6 Rat

Unigene: 499984 Human

Unigene: 412319 Mouse

Unigene: 431862 Mouse

Unigene: 26953 Rat

Omim: 603729 Human




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品圖片
Blank control: A549. Primary Antibody (green line): Rabbit Anti-SGPL1/FITC Conjugated antibody (bs-4188R-FITC) Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG-FITC . Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 0.1% PBST for 20 min at-20℃. The cells were then incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. The cells were stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed.
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