mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
精品日韩国产欧美在线观看,国产欧美综合精品一区,亚洲国产精品va一区二区三区
Rabbit Anti-PCGF4/BMI1/BF594 Conjugated antibody (bs-2999R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-2999R-BF594
英文名稱 Rabbit Anti-PCGF4/BMI1/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的組蛋白相關(guān)Bmi1抗體
別    名 B lymphoma Mo MLV insertion region; Bmi 1; BMI-1; MGC12685; Murine leukemia viral (bmi 1) oncogene homolog; Oncogene BMI 1; PCGF 4; PCGF4; Polycomb complex protein BMI 1; Polycomb complex protein BMI-1; Polycomb group ring finger 4; Polycomb group RING finger protein 4; RING finger protein 51; BMI1; RNF51; RAD18; BMI1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Chicken, Dog, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Bmi1/PCGF4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The Bmi1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway.
Polycomb group (PcG) genes are involved in the maintenance of cellular memory through epigenetic chromatin modifications. Recent studies have implicated a role for PcG genes in the self-renewal of hematopoietic stem cells (HSCs), a process in which cellular memory is maintained through cell division. Among the PcG genes, Bmi1 plays a central role in the inheritance of stemness, and its forced expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation. Involved in maintaining the transcriptionally repressive state of genes. Modifies chromatin, rendering it heritably changed in its expressibility.

Function:
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Subcellular Location:
Nucleus. Cytoplasm.

Post-translational modifications:
Monoubiquitinated. May be polyubiquitinated; which does not lead to proteasomal degradation.

Similarity:
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 100532731 Human

Entrez Gene: 648 Human

Entrez Gene: 12151 Mouse

Entrez Gene: 307151 Rat

Omim: 164831 Human

SwissProt: P35226 Human

SwissProt: P25916 Mouse

Unigene: 380403 Human

Unigene: 289584 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
日韩免费一级a毛片在线播放一级| 日韩激情精品久久久一区二区| 男人大鸡巴操女人的大逼| 好想大鸡巴插进阴道视频| 白丝袜子宫啊啊啊不要了| 97精品人妻人人做人人爽| 日本免费精品一区二区三区四区| 天天天天天干夜夜夜夜夜操| 国产成人精品久久久成人| 久久久久久久 亚洲精品| 中文字幕欧美人妻在线| 欧美日韩国产这里只有精品| 强奷很舒服好爽好爽| 免看一级a一片成人欧美| 大屌把女生逼逼操肿国产| 伊人久久丁香色婷婷啪啪| 狠狠五月激情综合去干网| 久久久一区二区三区日本| 国产亚洲精品一区久久| 成人黄色网破处在线播放| 日本高清一区二区三区在线观看| 国产欧美一区二区精品久久久| 国产高清乱码女大生AV| av中文字幕一区二区精品久久| 99热这里只有精品98| 爆乳1把你榨干在线观看| 夫妻性生活在线免费视频| 美性中文网中文字幕91| 亚洲国际精品一区二区| 美国女人抠插bbb| 操女人b直播软件| 西西大尺度无码免费视频| 亚洲精品成人无码app| 国产一二三四五自产| 午夜国产精品午夜福利网| 日韩在线视频不卡一区二区三区| 国产精品午夜小视频观看| 在线精品亚洲观看不卡欧| 欧美亚洲综合久久夜夜嗨| 欧美精品第一区二区三区| 日本熟人妻中文字幕在线|