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Rabbit Anti-PADI2/Gold Conjugated antibody (bs-11662R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11662R-Gold
英文名稱 Rabbit Anti-PADI2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的蛋白質(zhì)精氨酸亞型2抗體
別    名 PADI2 / PAD2; PAD 2; PAD2; PAD H19; PAD-H19; PADI 2; Padi2; PADI2 protein; PADI2_HUMAN; PDI 2; PDI2 antibody Peptidlyarginine deiminase type II; Peptidyl arginine deiminase II; Peptidyl arginine deiminase type II; Peptidylarginine deiminase II; Protein arginine deiminase; Protein arginine deiminase type 2; Protein arginine deiminase type II; Protein-arginine deiminase type II; Protein-arginine deiminase type-2; KIAA0994; OTTHUMP00000044625.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PADI2/PAD2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the deimination of arginine residues of proteins.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the protein arginine deiminase family.

Database links:

Entrez Gene: 11240 Human

Entrez Gene: 18600 Mouse

Entrez Gene: 29511 Rat

Omim: 607935 Human

SwissProt: Q96DA7 Human

SwissProt: Q9Y2J8 Human

SwissProt: Q08642 Mouse

SwissProt: Q75WD0 Mouse

SwissProt: P20717 Rat

Unigene: 33455 Human

Unigene: 2296 Mouse

Unigene: 469220 Mouse

Unigene: 98523 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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