| 產(chǎn)品編號(hào) | bs-11343R-APC |
| 英文名稱 | Rabbit Anti-Dynamin 3/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的酶動(dòng)力蛋白3抗體 |
| 別 名 | Dynamin III; testicular; DNM 3; DNM3; DNM3 protein; Dyn3; DYN3_HUMAN; Dyna III; DynaIII; dynamin 2; Dynamin; Dynamin family member; Dynamin testicular; Dynamin-3; Dynamin3; EC 3.6.5.5; KIAA0820; MGC70433; T dynamin; T-dynamin. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞類型標(biāo)志物 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 98kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Dynamin 3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Dynamin III is a microtubule-associated, force-producing GTPase that can form helical structures around the neck of vesicles. GTP hydrolysis-dependent extension of the helical structure releases the vesicle. Dynamin III contains a pair of phosphorylation sites at Ser 759 and Ser 763. Both 3.0 and 7.2 kb Dynamin III transcripts are detectable in brain. The 3.0 kb Dynamin III transcript is also detectable in testis. The 7.2 kb Dynamin III transcript is brain-specific for a protein thought to influence synaptogenesis in the CNS through recycling, neurotransmitter reuptake and growth factor-receptor signaling, in a thyroid hormone-dependent manner. A 6 kb antisense transcript (Dnm3os) contained within an intron of the mouse Dnm3 gene may be under transregulation by twist during mouse development. Dynamin III and Dnm3os transcripts overlap during embryogenesis and in adult tissues, except that Dynamin III is abundant in adult brain and testis whereas Dnm3os is abundant in embryos and gravid uterus. Function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis. Subcellular Location: Cytoplasm. Cytoplasm; cytoskeleton. Microtubule-associated. Similarity: Belongs to the dynamin family. Contains 1 GED domain. Contains 1 PH domain. Database links: Entrez Gene: 26052 Human Entrez Gene: 103967 Mouse Omim: 611445 Human SwissProt: Q9UQ16 Human SwissProt: Q8BZ98 Mouse Unigene: 654775 Human Unigene: 441620 Mouse Unigene: 11191 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
