| 產(chǎn)品編號 | bs-4948R-APC |
| 英文名稱 | Rabbit Anti-Bacillus anthraci protein/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的炭疽桿菌菌體蛋白抗體 |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 免疫學(xué) 細(xì)菌及病毒 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Whole cell protein of Bacillus anthraci |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Bacillus anthracis is an aerobic spore forming bacterium that causes anthrax, an acute infectious disease of cattle, sheep, goats, camels, antelopes and other herbivores. Infection can occur in humans when they are exposed to infected animals or tissue from infected animals via three routes: cutaneous, inhalation and gastrointestinal. B. anthracis spores persist in the soil for many years as they are resistant to heat, cold, radiation, desiccation, and disinfectants. In vivo, B anthracis produces a polypeptide (polyglutamic acid) capsule that protects it from phagocytosis. The virulence factors of B anthracis are its capsule and three component toxin, both encoded on plasmids. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 炭疽桿菌從損傷的皮膚、胃腸粘膜及呼吸道進(jìn)入人體后，首先在局部繁殖，產(chǎn)生毒素而致組織及臟器發(fā)生出血性浸潤、壞死和高度水腫，形成原發(fā)性皮膚炭疽、腸炭疽的肺炭疽等。當(dāng)機(jī)體抵抗力降低時，致病菌即迅速沿淋巴管及血管向全身擴(kuò)散，形成敗血癥和繼發(fā)性腦膜炎。皮膚炭疽因缺血及毒素的作用，真皮的神經(jīng)纖維發(fā)生變化，故病灶處常無明顯的疼痛感。炭疽桿菌的毒素可直接損傷血管的內(nèi)皮細(xì)胞，使血管壁的通透性增加，導(dǎo)致有效血容量減少，微循環(huán)灌注量下降，血液呈高凝狀態(tài)，出現(xiàn)DIC和感染性休克。 |
