mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  人才招聘  關于我們  聯(lián)系我們
国产日本亚洲一区二区三区,亚洲一区二区三区日韩在线,国产高清精品三区在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-PEG3/BF488 Conjugated antibody (bs-1870R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術支持:techsupport@m.p2b3.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1870R-BF488
英文名稱1 Rabbit Anti-PEG3/BF488 Conjugated antibody
中文名稱 BF488標記的PEG3蛋白抗體
別    名 Paternally-expressed gene 3 protein; Zinc finger and SCAN domain-containing protein 24; Kruppel-type zinc finger protein; paternally expressed 3; Paternally expressed gene 3; PEG3 protein; Pw1; Zn-finger protein Pw1; PEG3_HUMAN; Paternally-expressed gene 3 protein.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  細胞周期蛋白  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Horse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 175kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PEG3 (1535-1588aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Function:
Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. Possesses a tumor suppressing activity in glioma cells.

Subunit:
Homodimer. Interacts with SIAH1A and SIAH2. Interacts with TRAF2.

Subcellular Location:
Nucleus. Cytoplasm.

Tissue Specificity:
Brain, glial cells, astrocytes, embryo, placenta, testis, ovary and uterus. In the placenta it is found in the layer of villous cytotrophoblast cells while in the ovary it is found in the cells of the ovarian stroma including the thecal layers around the follicles. Expression is highly repressed in glioma cell lines.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 12 C2H2-type zinc fingers.
Contains 1 SCAN box domain.

Database links:

Entrez Gene: 18616 Mouse

Entrez Gene: 66549 Mouse

Entrez Gene: 246361 Rat

SwissProt: O54978 Mouse

SwissProt: Q3URU2 Mouse

SwissProt: Q61138 Mouse

SwissProt: Q6GQS0 Mouse

SwissProt: Q8R5N0 Mouse

SwissProt: Q9QX53 Mouse

Unigene: 7952 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PEG3蛋白是一種轉錄因子。在胰腺、腦組織、胎盤、卵巢、睪丸等組織中表達,PEG3蛋白位于細胞核內。PEG3也是一個凋亡促進因子并可能參與調節(jié)腫瘤壞死因子(TNF)信號傳導通路。
版權所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
99久久无色码中文字幕人妻| 欧美国产日韩精品77上位| 93国产精品久久久久久| 操久久久久久久久久久久久久久久久| 日韩精品一区二区av蜜桃| 久久久久国产精品老熟女| 欧美一区二区亚洲a一区二区| 日韩一区二区人妻9999| 五月婷婷六月丁香免费视频| 一区二区三区久久99精品| 亚洲国产精品成人综合色在线| 波多野结衣av一区二区| 精品久久久久久久久久中文幕| 精品人妻一区二区三区久久夜夜嗨| 国产精品青青青高清在线观看| 日韩激情av一区二区| 亚洲日韩欧美制服第一页| 日本在线一区二区免费| 91偷自产一区二区三区蜜尹臀| 亚洲国产精品久久久久网站| 日韩亚洲一区二区在线| 欧美日韩视频免费看| 亚洲中文无无码第21页| 亚洲av无码网站yw尤物| 99久久免费精品国产免费高清| 国产精品一区二区30p| 国产在线观看污污污网站| 亚洲欧美在线观看视频| 后进白嫩翘臀在线视频| 国产精品久久一二三区| 国产成人亚洲综合91精品首页| 日韩国产av一区二区| 日本一区二区三区影院| 日本一区二区三区中文字幕八戒视频| 99久久免费精品国产免费高清| 九色九九综合久久爱| 韩漫漫画在线免费看视频| 色婷婷久久久久久久久久| 亚洲成av一区二区三区| 精品久久久久一区二区三| 亚洲精品成人在线播放|