mm1313亚洲精品,欧美俄罗斯40老熟妇,欧美日韩在线观看视频在线,亚洲欧美国产激情综合在线

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲欧美日韩精品专区,中文字幕无码视频专区,欧美精品亚洲精品日韩精品一
Rabbit Anti-ITGA7/PE-Cy5.5 Conjugated antibody (bs-1816R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@m.p2b3.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@m.p2b3.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1816R-PE-Cy5.5
英文名稱 Rabbit Anti-ITGA7/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的整合素α7抗體
別    名 Integrin alpha-7 heavy chain; Integrin alpha-7 70 kDa form; Integrin alpha 7; a 7; alpha7; FLJ25220; INTEGRIN ALPHA 7; ITGA7; MGC105724; ITA7_HUMAN; Integrin alpha-7; Integrin α7; Integrin-α7.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70/101/125kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Integrin alpha-7 70 kDa form
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2009]

Function:
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

Subunit:
Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-7 associates with beta-1. Interacts with COMP.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Isoforms containing segment A are predominantly expressed in skeletal muscle. Isoforms containing segment B are abundantly expressed in skeletal muscle, moderately in cardiac muscle, small intestine, colon, ovary and prostate and weakly in lung and testes. Isoforms containing segment X2D are expressed at low levels in fetal and adult skeletal muscle and in cardiac muscle, but are not detected in myoblasts and myotubes. In muscle fibers isoforms containing segment A and B are expressed at myotendinous and neuromuscular junctions; isoforms containing segment C are expressed at neuromuscular junctions and at extrasynaptic sites. Isoforms containing segments X1 or X2 or, at low levels, X1X2 are expressed in fetal and adult skeletal muscle (myoblasts and myotubes) and cardiac muscle.

Post-translational modifications:
ADP-ribosylated on at least two sites of the extracellular domain in skeletal myotubes.
A 70 kDa form is created by proteolytic cleavage. Cleavage is elevated during myogenic differentiation and the cleaved form enhances cell adhesion and spreading on laminin.

DISEASE:
Defects in ITGA7 are the cause of muscular dystrophy congenital due to integrin alpha-7 deficiency (MDCI) [MIM:613204]. A form of congenital muscular dystrophy. Patients present at birth, or within the first few months of life, with hypotonia, muscle weakness and often with joint contractures.

Similarity:
Belongs to the integrin alpha chain family. Contains 7 FG-GAP repeats.

Database links:

Entrez Gene: 3679 Human

Entrez Gene: 16404 Mouse

Entrez Gene: 81008 Rat

Omim: 600536 Human

SwissProt: Q13683 Human

SwissProt: Q61738 Mouse

SwissProt: Q63258 Rat

Unigene: 524484 Human

Unigene: 54492 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.m.p2b3.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
黑人巨茎和中国美女视频| 欧美一区二区三区身体| 日韩人妻精品一区二区三区99| 日韩欧美综合一二三区| 精品免费福利片国产| 男生的小鸡鸡插进女生的桃子 里| 国产一级第一级毛片| 爆乳1把你榨干在线观看| 欧美日本欧美日本区一区二| 国产午夜高清无码一级片| 激烈18禁高潮视频免费| 91久久愉拍愉拍国产一区| 三级无码日B视频| 搬开女人下面使劲插视频| 国产成人精品免费视频全| 狂插美女大屁股在线观看| 日本亚欧乱色视频69室| 区国产精品搜索视频| 成年女人永久看片视频 | 日韩欧美人妻综合| 亚洲国产精品一区亚洲国产| 日日狠狠久久888av| 欧美亚洲另类天天综合网| 五月天国产成人免费视频| 大鸡巴干小逼视频| 日本中文字幕无人区一区二区| 欧美一区二区三区高清性群p| 久久国产精品二卡| 白嫩在线亚洲观看| 泰国无码AV片在线观看| 老湿机69福免费破解版| 日韩av大片一区二区三区| 亚洲综合区欧美一区二区| 18岁以下禁看美女的胸| 日韩精品人妻一区二区免费| 国产裸模大尺度私拍视频| 伊人成人精品在线| 99国产精品一区二区| 国产成人无码91精品一区| 国产精品亚洲一区二区三区极品| 国产一区二区在线观看精品|