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Rabbit Anti-BAI1/PE-Cy3 Conjugated antibody (bs-7513R-PE-Cy3)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7513R-PE-Cy3
英文名稱 Rabbit Anti-BAI1/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的腦特異性血管生成抑制蛋白1抗體
別    名 BAI 1; BAI-1; Brain specific angiogenesis inhibitor 1; mKIAA4089; KIAA4089; R75078; B830018M07Rik; BAI1_HUMAN  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 心血管  細(xì)胞生物  免疫學(xué)  血管內(nèi)皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 170kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BAI1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
BAI 1 protein is likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. It may function in cell adhesion and signal transduction in the brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues.

Function:
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain.

Subunit:
Interacts with ELMO1 and DOCK1. When bound to ELMO1 and DOCK1, it may act as a module to promote the engulfment. Interacts with MAGI1, MAGI3, BAIAP2 and PHYHIP.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Note=Likely to be concentrated at cell-cell adhesion sites.

Tissue Specificity:
Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. No expression in astrocytes.

Post-translational modifications:
The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.

Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain.
Contains 5 TSP type-1 domains.

Database links:

Entrez Gene: 524070 Cow

Entrez Gene: 575 Human

Entrez Gene: 107831 Mouse

Entrez Gene: 362931 Rat

Omim: 602682 Human

SwissProt: O14514 Human

SwissProt: Q3UHD1 Mouse

Unigene: 194654 Human

Unigene: 43133 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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