| 產(chǎn)品編號 | bs-6300R-BF488 |
| 英文名稱 | Rabbit Anti-TEM7R/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的腫瘤血管內(nèi)皮標(biāo)記相關(guān)蛋白質(zhì)7抗體 |
| 別 名 | Tumor endothelial marker 7 related protein; Plexin domain containing 2; Plexin domain containing protein 2; Plexin domain-containing protein 2; PLXDC 2; plxdc2; PXDC2_HUMAN; TEM7R; Tumor endothelial marker 7-related protein. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 血管內(nèi)皮細(xì)胞 腫瘤細(xì)胞生物標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 56kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TEM7R. |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: TEM7R also known as PLXDC2 is a 529 amino acid single-pass type I membrane protein containing one PSI domain and belonging to the plexin family. Localizing to membrane, TEM7R is expressed in endothelial cells of the stroma, as well as in limbs, lung buds, developing heart, spinal cord and dorsal root ganglia. TEM7R interacts with cortactin and may play a role in tumor angiogenesis. Existing as three alternatively spliced isoforms, the gene encoding TEM7R maps to human chromosome 10p12.31. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. Function: May play a role in tumor angiogenesis. Subunit: Interacts with CTTN. Subcellular Location: Membrane; Single-pass type I membrane protein Tissue Specificity: Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue. Similarity: Belongs to the plexin family. Contains 1 PSI domain. Database links: Entrez Gene: 84898 Human Entrez Gene: 67448 Mouse Omim: 606827 Human SwissProt: Q6UX71 Human SwissProt: Q9DC11 Mouse Unigene: 658134 Human Unigene: 313938 Mouse Unigene: 394655 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
